Marmara Eczacýlýk Dergisi - 2013; 17(3) - Current Issue Marmara Pharmaceutical Journal - RSS feed of Current Issue September 2013 Marmara Pharmaceutical Journal <![CDATA[Assessing of public awareness concerning unused medicines in households: a pilot study]]> 2013-09-01 Marmara Pharmaceutical Journal 3 17 159 2013-09-01 155 Original Article <![CDATA[An approach to the intelligent drug delivery systems: Thermo-responsive membrane for pulsatile drug delivery]]> 2013-09-01 Marmara Pharmaceutical Journal 3 17 164 2013-09-01 160 Original Article <![CDATA[Comparative bone uptake study of alendronate sodium from vaginal suppositories prepared with polyethylene glycol and massa estarinum bases]]> 99m Tecnetium Pertechnetate ( 99m Tc) by direct method. Radiochemical purity and stability of 99m Tc-ALD was performed with chromatographic studies. 99m Tc-ALD containing suppositories were prepared with ME and PEG bases. Physical properties of suppositories were evaluated. The physicochemical diffusion study was carried out to compare the release of ALD from different suppository bases. The bone uptake of 99m Tc-ALD was observed by gamma scintigraphy studies. 99m Tc-ALD containing suppositories were administrated to rabbits via vaginal route. The scintigraphic images were obtained with a gamma camera at different time intervals up to 240 minutes. According to our studies, radiochemical purity of 99m Tc-ALD was observed more than 95% up to 6 hours. At 240 minutes of physicochemical diffusion studies, released ALD has 0.620 ± 0.091 mm and 10.465 ± 0.651 mm diameter zone from ME and PEG base suppositories respectively. According to the gamma scintigraphy studies, although no bone uptake observed after ME suppositories application, rabbit's bones were clearly visible after PEG suppositories applied. The results of physicochemical diffusion and gamma scintigraphy studies were found compatible in each other.]]> 2013-09-01 Marmara Pharmaceutical Journal 3 17 169 2013-09-01 165 Original Article <![CDATA[Foam fractionation in recovery of captopril]]> 2013-09-01 Marmara Pharmaceutical Journal 3 17 174 2013-09-01 170 Original Article <![CDATA[The evaluation of prescription dispensing scores of the pharmacy students before and after the problem-based “rational drug use” course: Results of the two years' experience]]> 1,2, Rümeysa Demirdamar]]> 2013-09-01 Marmara Pharmaceutical Journal 3 17 180 2013-09-01 175 Original Article <![CDATA[Development of a New and Efficient Synthesis Method of 1,2,4-Triazole-5- Thione Derivatives]]> 2013-09-01 Marmara Pharmaceutical Journal 3 17 186 2013-09-01 181 Original Article <![CDATA[Synthesis and antimicrobial activity of some pyrazoline derivatives bearing amide moiety]]> 1 H-NMR, 13 C-NMR and FAB+- MS spectral data and elemental analyses. The synthesized compounds were screened for their antimicrobial activities. All compounds exhibited the highest antibacterial activity against P. aeruginosa. All compounds except compounds 1-(chloroacetyl)-3-(2-furanyl)-5-(4- chlorophenyl)-2-pyrazoline and 1-(chloroacetyl)-3-(2-thienyl)-5-(3,4-methylenedioxyphenyl)- 2-pyrazoline are more effective than ketoconazole against C. albicans, whereas compounds 1-(chloroacetyl)-3-(2-furanyl)-5-(4-chlorophenyl)-2-pyrazoline, 1-(chloroacetyl)-3-(2-thienyl)- 5-(3,4-methylenedioxyphenyl)-2-pyrazoline and ketoconazole showed the same level of antifungal activity against C. albicans.]]> 2013-09-01 Marmara Pharmaceutical Journal 3 17 192 2013-09-01 187 Original Article